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PLGA Nanoparticles, Magnetic

PLGA Nanoparticles, Magnetic

Description

Our single-layer poly (lactic-co-glycolic acid) (PLGA) nanoparticles form nanostructures with a hydrophobic core encapsulated inside a hydrophilic shell. Magnetic nanoparticles are encapsulated inside the hydrophobic core. PLGA surface contains COOH groups that can be used for EDC/NHS based bioconjugation. Optional surface modifications include methoxy PEG (improves in vivo blood half-life) and PEG-Azide (can be used to covalently attach biomolecules by click chemistry)

 

Features

  • Made with FDA approved biocompatible and biodegradable PLGA polymer.
  • Conjugation-ready for covalent attachment of biomolecules.
  • High degree of monodispersity.
  • Can be pulled down by application of magnetic force.
  • (Optional) Incorporation of Methoxy-PEG minimizes non-specific protein adsorption. This increase nanoparticle in-vivo blood half-life.
  • (Optional) Incorporation of Azide-PEG allows conjugation of proteins and small molecules by click chemistry.

 

Applications

  • Magnetic nanoparticles for in-vivo targeting.
  • Probes for MRI imaging for in vitro and in vivo applications.
  • Magnetic probes for magnetic cell and small molecule pulldown.
  • In vitro and in vivo delivery of proteins and small molecules.

 

Product is supplied as lyophilized powder.

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