Dextran CLIO Magnetic Nanoparticles - Amine

General Information

Amine-functionalized Dextran coated crosslinked iron oxide nanoparticles (CLIO-NH2) have 1-3 superparamagnetic Fe3O4 iron oxide cores (8-10 nm in diameter) imbedded within the matrix of dextran sugar strands of 40 kDa or 70 kDa size. Dextran strands are crosslinked to prevent their disassociation, ensuring long-term biological stability. Dextran surface has been functionalized with Amine NH2 groups.



  • Highly biocompatible, non-toxic
  • Long term stable under physiological conditions
  • 40 kDa and 70 kDa dextran coats are available
  • Highly magnetic
  • Can be easily conjugated to NHS-activated ligands



  • In vitro and in vivo magnetic labels for cells and tissues
  • Magnetic cell separation
  • Probes for MRI



  • Iron Oxide Core Diameter: 8 – 10 nm
  • Hydrodynamic Diameter: 50 – 110 nm
  • Polydispersity Index (PDI): < 0.3
  • Nanoparticle Charge: Between 1 and 10 mV
  • Magnetization:  5 – 30 emu/g (room temperature)
  • Shelf life: > 1 year (4°C storage)
  • Supplied as liquid suspension in PBS

Dextran CLIO Magnetic Nanoparticles - Amine

Dextran Size
Volume (@ 5 mg/mL Fe)
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