Dextran CLIO Magnetic Nanoparticles - Biotin
General Information
Biotin functionalized Dextran coated crosslinked iron oxide nanoparticles (CLIO-BIOT) have 1-3 superparamagnetic Fe3O4 iron oxide cores (8-10 nm in diameter) imbedded within the matrix of dextran strands of 40 or 70 kDa in size. Dextran strands are crosslinked to prevent their disassociation, ensuring long-term stability. Biotin is covalently conjugated to the nanoparticle surface.
Features
- Highly magnetic
- Highly biocompatible, non-toxic
- Long term stable under physiological conditions
- 40 kDa and 70 kDa dextran coats are available
- Easy loading of biomolecules through Streptavidin-Biotin interaction
Applications
- In vitro and in vivo magnetic labels for cells and tissues
- Magnetic cell separation
- Probes for MRI
Specifications
- Iron Oxide Core Diameter: 8 – 10 nm
- Hydrodynamic Diameter: 60 – 80 nm
- Polydispersity Index (PDI): < 0.25
- Magnetization: 5 – 30 emu/g (room temperature)
- Shelf life: > 1 year (4°C storage)
- Supplied as liquid suspension in water
Product Documentation