Dextran CLIO Magnetic Nanoparticles - Streptavidin, Fluorescent Dye

General Information

Fluorescent, Streptavidin functionalized Dextran coated crosslinked iron oxide nanoparticles (CLIO-STRP-D) have 1-3 superparamagnetic Fe3O4 iron oxide cores (8-10 nm in diameter) imbedded within the matrix of dextran strands of 40 or 70 kDa in size. Dextran strands are crosslinked to prevent their disassociation, ensuring long-term stability. Streptavidin and fluorescence dye are covalently conjugated to the nanoparticle surface.

 

Features

  • Superparamagnetic
  • Fluorescently labeled (AFDye 488, AFDye 555, AFDye 647, or IR750 dye)
  • Highly biocompatible, non-toxic
  • Long term stable under physiological conditions
  • 40 kDa and 70 kDa dextran coats are available
  • Easy loading of biomolecules such as Antibodies through Streptavidin-Biotin interaction

 

Applications

 

  • In vitro and in vivo dual magnetic and fluorescence labels for cells and tissues.
  • Magnetic, fluorescence, or dual cell separation.
  • Probes for MRI.

 

Specifications

  • Fluorescent Dye:
    • AFDye 488 (AlexaFluor 488 analog, Abs/Em = 490/525, Filter set: FITC)
    • AFDye 555 (AlexaFluor 555 analog, Abs/Em = 555/580, Filter set: TRITC)
    • AFDye 647 (AlexaFluor 647 analog, Abs/Em = 650/665, Filter set: Cy5)
    • IR750 (IRDye 750 analog, Abs/Em = 756/776, Filter set: Cy7)
  • Iron Oxide Core Diameter: 8 – 10 nm
  • Hydrodynamic Diameter: 70 – 130 nm
  • Polydispersity Index (PDI): < 0.3
  • Magnetization:  5 – 30 emu/g (room temperature)
  • Shelf life: > 1 year (4°C storage)
  • Supplied as liquid suspension in sterile PBS

Dextran CLIO Magnetic Nanoparticles - Streptavidin, Fluorescent Dye

$225.00Price
Dextran Size
Fluorescent Dye Label
Volume (@ 5 mg/mL Fe)
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